Genie in a bottle: controlled release helps tame natural polypharmacology?

Hydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide

Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...

Hydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide

Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...

Natural selection in a bottle.

The study of natural selection in laboratory systems undergoing experimental evolution can provide important insights into the relationship between natural selection and adaptation. We studied selection on the norm of reaction of age at first reproduction in a laboratory population of Drosophila melanogaster. This population had been selected on a discrete generation schedule in the laboratory ...

Stent magic! The genie has escaped from the bottle.

A response to injury leading to intimal thickening and subsequent " restenosis " has limited the clinical eYciency of percutaneous coronary interventions ever since they have been used to treat symptomatic coronary artery disease. During the recent two decades a lot has been learned about the pathophysiology of the response to injury following different kinds of interventions. The predominant m...

Genie in a Bottle? Assessing Managerial Opportunism in International Securities Transactions